Tranzyme Pharma is refocusing efforts on TZP-102, it’s diabetic gastroparesis drug treatment, after the failure of it’s flagship drug Ulimorelin.
Tranzyme Pharma & the FDA were not happy with the results of the Phase III trial results for Ulimorelin. Ulimorelin is similar to Tranzyme’s other drug TZP-102, in that it uses a ghrelin receptor agonist to stimulate motility in the gut. The drug was meant to treat people with delayed gastrointenstinal recovery / post operative ileus which is most often associated with gastrointestinal or gynecological surgery. Continue reading “Tranzyme Still Optimistic About Gastroparesis Drug Despite Stumbling Blocks” »
A dairy cow has tested positive for Bovine Spongiform Encephalopathy on a California farm.
USDA testers found the infected cow while doing regular testing. The cow had died before the tests were done, but according to it’s owner it was not exhibiting symptoms of Mad Cow Disease beforehand. USDA testers have said that the cow was infected with an atypical form of Mad Cow Disease which was not obtained from eating infected cattle feed. Continue reading “Mad Cow Disease Spotted In California” »
A Chinese research study investigated if human derived stem cells can treat induced colitis in mice.
The researchers were specifically interested in studying human umblical cord mesenchymal stem cells which have a poor immunogenic response. This means they are less likely to trigger the immune system into attacking them. At the same time mesenchymal stem cells have potent immunosuppressive qualities, in that they suppress the autoimmune system response. Given these properties, they are being investigated extensively for treatment in those who have autoimmune related diseases. Continue reading “Umbilical Stem Cells May Offer Treatment For Inflammatory Bowel Diseases” »